Department of Chemistry, Qom Branch, Islamic Azad University, Qom, Iran
Abstract
In this research, a series of 2,3-disubstituted quinazoline-4(3H)-one derivatives has been synthesized in high selectivity by one-pot multicomponent reaction through reflux method. The performance of various techniques was studied comparatively on the attributes of the product and catalyst by applying different characterized tests. The copper oxide/graphene oxide composites (CuO/GO nanocomposite) were well prepared using a co-precipitation method and characterized to confirm their structure and composition. According to the obtained data, the reflux method provides a mild process, and as a result, time and energy are saved. The reaction was efficiently promoted by 20 mg of CuO/GO composite as a robust and heterogeneous nano-sized catalyst. As expected, the proposed heterogeneous nano-sized catalyst that was designed and prepared, performed well promoting the studied products (up to 93%). High to excellent yield, saving energy and time, chemical/thermal stability, eco-friendliness, and reusability of nanocatlyst (5 runs) are several of the outstanding advantages of this research.
Reza Farhang, M. , Fadaeian, M. , Reza Najafi, G. and Sharif, M. S. (2025). Preparation of 2,3-disubstituted quinazoline-4(3H)-one derivatives in the presence of CuO/graphene oxide as an effective catalyst. Journal of Nanostructures, (), -.
MLA
Reza Farhang, M. , , Fadaeian, M. , , Reza Najafi, G. , and Sharif, M. S. . "Preparation of 2,3-disubstituted quinazoline-4(3H)-one derivatives in the presence of CuO/graphene oxide as an effective catalyst", Journal of Nanostructures, , , 2025, -.
HARVARD
Reza Farhang, M., Fadaeian, M., Reza Najafi, G., Sharif, M. S. (2025). 'Preparation of 2,3-disubstituted quinazoline-4(3H)-one derivatives in the presence of CuO/graphene oxide as an effective catalyst', Journal of Nanostructures, (), pp. -.
CHICAGO
M. Reza Farhang , M. Fadaeian , G. Reza Najafi and M. S. Sharif, "Preparation of 2,3-disubstituted quinazoline-4(3H)-one derivatives in the presence of CuO/graphene oxide as an effective catalyst," Journal of Nanostructures, (2025): -,
VANCOUVER
Reza Farhang, M., Fadaeian, M., Reza Najafi, G., Sharif, M. S. Preparation of 2,3-disubstituted quinazoline-4(3H)-one derivatives in the presence of CuO/graphene oxide as an effective catalyst. Journal of Nanostructures, 2025; (): -.
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