1
Babol University of Medical Sciences, pramedicine Faculty, Anesthesiology and Operation Department, Babol, Iran
2
Department of Radiopharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
10.7508/jns.2016.01.014
Abstract
In this work we synthesized of mesoporous silica nanoparticles and functionalized with 3-aminopropyltriethoxysilane to improve the loading and release of ibuprofen bonded to 3-aminopropyltriethoxysilane. sample were characterized by Fourier transform infrared spectroscopy, Scanning electron microscopy , X-ray diffraction, and ultraviolet-visible. the Fourier transform infrared spectroscopy result demonstrate that organic group were successfully functionalized onto mesoporous silica nanoparticles. Then, we investigate of the adsorption and release of ibuprofen as a drug delivery system in simulated body fluid. The result demonstrates that high adsorption capacity for drug with functionalized sample and slower drug release rate was achieved.
Mortazavi,Y and Ghoreishi,S M . (2016). Synthesis of Mesoporous Silica and Modified as a Drug Delivery System of Ibuprofen. Journal of Nanostructures, 6(1), 86-89. doi: 10.7508/jns.2016.01.014
MLA
Mortazavi,Y , and Ghoreishi,S M . "Synthesis of Mesoporous Silica and Modified as a Drug Delivery System of Ibuprofen", Journal of Nanostructures, 6, 1, 2016, 86-89. doi: 10.7508/jns.2016.01.014
HARVARD
Mortazavi Y, Ghoreishi S M. (2016). 'Synthesis of Mesoporous Silica and Modified as a Drug Delivery System of Ibuprofen', Journal of Nanostructures, 6(1), pp. 86-89. doi: 10.7508/jns.2016.01.014
CHICAGO
Y Mortazavi and S M Ghoreishi, "Synthesis of Mesoporous Silica and Modified as a Drug Delivery System of Ibuprofen," Journal of Nanostructures, 6 1 (2016): 86-89, doi: 10.7508/jns.2016.01.014
VANCOUVER
Mortazavi Y, Ghoreishi S M. Synthesis of Mesoporous Silica and Modified as a Drug Delivery System of Ibuprofen. jns.kashanu.ac.ir. 2016;6(1):86-89. doi: 10.7508/jns.2016.01.014
