Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, I.R.Iran
Abstract
Green chemistry primarily focuses on preventing pollution by designing chemical products and processes that are environmentally friendly. Developing greener methods for synthesizing heterocyclic compounds remains a significant and motivating challenge in organic synthesis The present investigation in organic and medicinal chemistry focuses on nitrogen-containing heterocycles, particularly benzimidazole derivatives. Benzimidazoles and their derivatives reflect their extensive pharmacological activities, and various methods have been developed for synthesis and application of benzimidazole derivatives. This research details a green and sustainable approach for synthesis of benzimidazole derivatives, vital nitrogen-containing heterocycles in pharmaceuticals. Traditionally, these are formed from ortho-phenylenediamine and an aldehyde under harsh acidic conditions. Our research focuses on their thermal synthesis using a newly developed Go@Fe₃O₄/Ag₂O catalyst. This magnetic nanocatalyst (MNC) offers excellent performance and reusability, enabling eco-friendly solvent use, easy magnetic separation, straightforward and cost-effective fabrication. Thermal synthesis, often solvent-free, provides an efficient alternative condition. Reaction progress was monitored via TLC, with structural integrity confirmed by FT-IR and 1H NMR. The catalyst was comprehensively characterized by XRD, FTIR, EDX, BET, FESEM, and VSM.
Hassanzadeh Kalali, F. and Bamoniri, A. (2025). Design, preparation, and characterization of Go@Fe₃O₄/ Ag₂O for the synthesis of benzimidazoles using thermal condition. Journal of Nanostructures, (), -.
MLA
Hassanzadeh Kalali, F. , and Bamoniri, A. . "Design, preparation, and characterization of Go@Fe₃O₄/ Ag₂O for the synthesis of benzimidazoles using thermal condition", Journal of Nanostructures, , , 2025, -.
HARVARD
Hassanzadeh Kalali, F., Bamoniri, A. (2025). 'Design, preparation, and characterization of Go@Fe₃O₄/ Ag₂O for the synthesis of benzimidazoles using thermal condition', Journal of Nanostructures, (), pp. -.
CHICAGO
F. Hassanzadeh Kalali and A. Bamoniri, "Design, preparation, and characterization of Go@Fe₃O₄/ Ag₂O for the synthesis of benzimidazoles using thermal condition," Journal of Nanostructures, (2025): -,
VANCOUVER
Hassanzadeh Kalali, F., Bamoniri, A. Design, preparation, and characterization of Go@Fe₃O₄/ Ag₂O for the synthesis of benzimidazoles using thermal condition. Journal of Nanostructures, 2025; (): -.
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