Department of Biology, College of Education for Pure Science, Ibn Al-Haitham, University of Baghdad, Iraq College of Dentistry, Al-Iraqi University, Iraq
Abstract
The liver is more susceptible to the harmful effects of toxicological substances like carbon tetrachloride (CCL4). CCL4 releases free radicals that damage liver, promote lipid peroxidation, and release free radicals, which antioxidants can be administered to prevent, such as bromelain. This research aimed to investigate if bromelain antioxidants affect the CCL4-induced histopathological characteristics of albino mice livers. A total of 49 animals were divided into seven equal groups. Liver was harvested from mice to assess Histopathological changes, and immunohistochemically changes (Caspase-9). The current study showed a better protective effect in mice dosed with bromelain solution loaded on gold nanoparticles.The liver is more susceptible to the harmful effects of toxicological substances like carbon tetrachloride (CCL4). CCL4 releases free radicals that damage liver, promote lipid peroxidation, and release free radicals, which antioxidants can be administered to prevent, such as bromelain. This research aimed to investigate if bromelain antioxidants affect the CCL4-induced histopathological characteristics of albino mice livers. A total of 49 animals were divided into seven equal groups. Liver was harvested from mice to assess Histopathological changes, and immunohistochemically changes (Caspase-9). The current study showed a better protective effect in mice dosed with bromelain solution loaded on gold nanoparticles.
Ibrahim Ali, H., & H. Mutlak, B. (2024). Antioxidant effect of bromelain-loaded gold nanoparticles on albino mice Liver induced by CCL4: Histopathological and Immunohistochemical study. Journal of Nanostructures, (), -.
MLA
Haneen Ibrahim Ali; Baydaa H. Mutlak. "Antioxidant effect of bromelain-loaded gold nanoparticles on albino mice Liver induced by CCL4: Histopathological and Immunohistochemical study", Journal of Nanostructures, , , 2024, -.
HARVARD
Ibrahim Ali, H., H. Mutlak, B. (2024). 'Antioxidant effect of bromelain-loaded gold nanoparticles on albino mice Liver induced by CCL4: Histopathological and Immunohistochemical study', Journal of Nanostructures, (), pp. -.
VANCOUVER
Ibrahim Ali, H., H. Mutlak, B. Antioxidant effect of bromelain-loaded gold nanoparticles on albino mice Liver induced by CCL4: Histopathological and Immunohistochemical study. Journal of Nanostructures, 2024; (): -.
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