Effect of ZrO2 loading on monomer concentrations of methyl methacrylate and ethyl methacrylate in resin used for the manufacture of removable denture bases

Document Type : Research Paper

Authors

Belgorod State University Pobedy str., 85, Belgorod, 308015 Russia

Abstract

The study was designed to assess the change in flexural strength of unmodified heat cure denture base polymer resin on reinforcement with ZrO2 nanoparticles. The Federal Law No. 3-FZ of January 8, 1998 on Narcotic Drugs and Psychotropic Substances (Russian) establishes the presence of methyl methacrylate, a precursor of the synthetic opioid analgesic 3-methylfentanyl, in the resin monomers for removable denture bases Ftorax, Belacryl hot-curing methyl methacrylate (Belacryl-MGO). Fulfilling the statutory requirements of the licensed circulation of precursors, Dental Materials Manufacturers and Healthcare Facilities incur additional expenses that increase the prime cost of materials and treatment. The hot cure technology does not exclude the probability of migration of methyl methacrylate out into the oral fluid, which leads to oral toxicity that complicates the rehabilitation of patients, and in some cases necessitates repeated dental prosthetics using other basic materials. The high demand for removable laminar prostheses, and the need to exclude resin from treatment algorithms, with a technology based on licensed circulation of methyl methacrylate, a precursor of the synthetic opioid analgesic 3-methylfentanyl, the need to develop and evaluate the toxic potential of ethyl methacrylate resin. The article presents the dynamics of the concentration of methyl methacrylate and ethyl methacrylate monomers in aqueous extracts from base resin samples Ftorax, Belacryl-MGO and Belacryl hot-curing ethyl methacrylate (Belacryl-EGO) based on Reversed Phase High Performance Liquid Chromatography (RP HPLC). The concentration was evaluated on days 1, 3, 7 and 14 of the samples being in distilled water.

Keywords

Journal of Nanostructures

Articles in Press, Accepted Manuscript
Available Online from 11 March 2022

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