CHITOSAN/ HAP NANOPARTICLES: ANTIBACTERIALSTUDY

Articles in Press

Document Type : Research Paper

Authors

1 Nanotechnology and Advanced Materials Research Center, University of Technology, Iraq

2 College of science for women, University of Babylon

3 Civil Engineering, University of Technology-Iraq.

4 Middle Technical University, Kut-Technical Institute –Iraq

Abstract

Combination of organic polymer with Hydroxyapatite (HAP) credible composites would be used widely in biomaterial and environmental engineering. The surface chemical characterization of chitosan/ Hydroxyapatite nanoparticles (HAPNPs) was investigated by X-ray diffraction (XRD) and Fourier transform infrared (FTIR). Morphology images of composite samples were detected by Transmission electron microscopic (TEM) and Field emission scanning microscope (FESM). These results were confirmed homogeneous structure, and interaction between the chitosan and HAP. The antibacterial responses to the hydroxyapatite/chitosan matrix coatings were studied as a function of hydroxyapatite concentration. The results of antibacterial test showed that the antimicrobial activity was proportional to the concentration of hydroxyapatite nanoparticles. The synthesis process for the proposed nano hydroxyapatite is also very simple, low cost, and friendly environmental. Moreover, All the above advantages indicated the intriguing potential of the samples can be used in biomedical and practical wastewater treatment applications.
In this study low cost technique was used to produce HAPNPs and mixing with chitosan at different percentage. The morphology testing shows unique structure for CS/HA{NPs and cluster for HAPNPs alone. It showed a good antibacterial activity against E-coli and and Staphylococcus aureus bacterial.

Keywords

Journal of Nanostructures

Articles in Press, Accepted Manuscript
Available Online from 11 March 2022

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