University of Kashan Journal of Nanostructures 2251-7871 2 2 2012 06 01 Nano-SbCl5/SiO2 as an Efficient Catalyst for One-Pot Synthesis of 2, 4, 5-Trisubstituted Imidazoles Under Solvent- Free Condition 221 226 5373 10.7508/jns.2012.02.010 EN A. Bamoniri Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167 Kashan, I. R. Iran. S. Rohani Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167 Kashan, I. R. Iran. Journal Article 2014 05 12 A general synthetic route to the synthesis of imidazoles has been developed using nano SbCl5/SiO2 under solvent-free conditions. The multi-component reactions of aldehydes, benzil and ammonium acetate were carried out to afford some trisubstituted imidazole derivatives. This method provides several advantages like simple work-up, environmentally benign, and shorter reaction times along with high yields. The mentioned nano catalyst was investigated by SEM, TEM and XRD. Meanwhile, structures of trisubstituted imidazoles were elucidated by FT-IR, 1 H NMR and 13 C NMR spectra. https://jns.kashanu.ac.ir/article_5373_b4814b911f253356faa9d53a3dbf6bd2.pdf