University of Kashan Journal of Nanostructures 2251-7871 1 3 2011 07 01 Structural studies on the interaction of nano-SiO2 with lysozyme 205 212 5310 10.7508/jns.2011.03.004 EN B. Shareghi Department of Biology, University of Shahrekord, P.O. Box: 115, Shahrekord, I. R. of Iran S. Farhadian Department of Biology, University of Shahrekord, P.O. Box: 115, Shahrekord, I. R. of Iran M. Salavati-Niasari Institute of Nano Science and Nano Technology, University of Kashan,Kashan,P.O.BOX.87317-51167,I. R. of Iran Journal Article 2014 05 05 The interaction between nano-SiO2 and lysozyme was investigated by the method of UV-Visible  detection and fluorescence spectroscopic techniques. The thermal denaturation of lysozyme has been investigated in the presence and absence of nano-SiO2 over the temperature range (293-373) K in different buffers and pH values, using temperature scanning spectroscopy. The presence of nano-SiO2 caused the destabilization of lysozyme resulting in a decrease in the temperature of unfolding with an increase in nano-SiO2 concentration. https://jns.kashanu.ac.ir/article_5310_7a95e2b2ca2707a4701b1ae0e578abce.pdf