University of Kashan Journal of Nanostructures 2251-7871 1 3 2011 07 01 Determination of epinephrine in the presence of uric acid and folic acid using nanostructure-based electrochemical sensor 181 190 5307 10.7508/jns.2011.03.001 EN M. Mazloum-Ardakani Department of Chemistry, Faculty of Science, Yazd University, Yazd, I. R. Iran H. Beitollahi Department of Chemistry, Faculty of Science, Yazd University, Yazd, I. R. Iran B. B. F. Mirjalili Department of Chemistry, Faculty of Science, Yazd University, Yazd, I. R. Iran A. Akbari Department of Chemistry, Faculty of Science, Yazd University, Yazd, I. R. Iran Journal Article 2014 05 05 Fabrication and electrochemical characterization of a sensor for the determination of epinephrine (EP), uric acid (UA) and folic acid (FA) is described. The sensor  was prepared using carbon paste electrode (CPE) modified with 3,4-dihydroxybenzaldehyde-2,4-dinitrophenylhydrazone (DDP) and carbon nanotubes (CNTs), which makes the modified electrode highly sensitive for the electrochemical detection of these compounds. Cyclic voltammetry (CV) at various scan rates was used to probe the fabrication and characterization of the modified electrode. In order to characterize these new modified electrode, the electroanalytical response was evaluated for EP performing cyclic voltammetry, differential pulse voltammetry and chronoamperometry experiments. Under the optimum pH of 7.0, the oxidation of EP occurs at a potential about 215 mV less positive than that of the unmodified CPE. Differential pulse voltammetry (DPV) of EP at the modified electrode exhibited two linear dynamic ranges with a detection limit (3σ) of 70 nM. DPV was used for simultaneous determination of EP, UA and FA at the modified electrode, and quantification of EP in some real samples by the standard addition method. https://jns.kashanu.ac.ir/article_5307_efa5a629d33dd52806e4f1dc056385eb.pdf