University of Kashan Journal of Nanostructures 2251-7871 14 4 2024 10 01 Evaluation of Cadmium Oxide Nanoparticles’ Antibacterial and Antifungal Potential 1191 1196 114637 10.22052/JNS.2024.04.019 EN Zainab Alag Hasan College of Nursing, University of Basrah, Basra, Iraq Rashid Rahim Hateet College of Nursing, University of Mesan, Mesan, Iraq Abdulameer Abdullah Al-Musawi College of Nursing, University of Basrah, Basra, Iraq Journal Article 2024 07 04 Pathogenic microorganisms that are resistant to antibiotics have made it necessary to look for new antimicrobials. Nowadays, employing nanoparticles as therapeutic agents may be novel and promising. Cadmium Oxide (CdO) nanoparticles were found to have antibacterial efficacy against bacteria that tested negative for the gram stain, such as Pseudomonas aeruginosa, Salmonella typhi, Morganella morganii, Klebsiella pneumoniae, Proteus vulgaris, and Serratia spp. They were also shown to have antimicrobial activity against bacteria that were positive for the gram stain, including Streptococcus, Staphylococcus aureus (ATCC 25923) measured between (10.0 to 18.5) mm, while antifungal agents were evaluated on Candida albicans and Candida kruzi with inhibition zones of 10.0 and 10.5 mm. The well diffusion approach was used to measure the nanoparticles’ activity. The evaluated CdO nanoparticles had a concentration range of 100 mg/ml, and the activity was assessed by measuring the zone of inhibition. The results of the qualitative test included the determination of the MIC and MBC values. In the MIC range of 0.078-0.52mg/ml, CdO nanoparticles demonstrated good efficacy. Staphylococcus aureus demonstrated the maximum activity (MIC 0.078 mg/ ml), whereas E. coli displayed low susceptibility (MIC 0.83 mg/ ml). The cadmium oxide nanoparticles were studied using scanning electron microscopy with EDAX analysis and X-ray diffraction. https://jns.kashanu.ac.ir/article_114637_c763021865f2139d37a2da49536947b9.pdf