University of Kashan Journal of Nanostructures 2251-7871 Articles in Press 2023 07 30 Study the properties of Ti alloy by addition Nb and Si alloying elements for Orthopedic implant 113858 EN Niveen Jamal Abdulkader Materials Engineering Department, University of Technology, Zip code:10066, karada, Baghdad, Iraq, E-mail: 130012@uotechnology.edu.iq Payman Sahbah Ahme Manufacturing & Industrial Engineering Dept., Faculty of Engineering, Koya University, Zip code:46017, Koya KOY45, Kurdistan Region- F.R.Iraq , E-mail: payman.suhbat@koyauniversity.org. Shahad Abduladheem Jabbar Materials Engineering Department, University of Technology, Zip code:10066, karada, Baghdad, Iraq, E-mail: Shahad1992.sh@gmail.com Journal Article 2022 11 23 Investigations were done on the microstructure, mechanical characteristics, and biocompatibility of vacuum-sintered Ti 5Nb and Ti 5Si binary system alloys. The findings showed that two alloys included alpha phase. The inclusion of Nb and Si Nano powder enhanced the hardness of the alloys, which varied from 387 HV (Ti-5Nb) to 395 HV (Ti–5Si). When compared to CP Ti, Nb and Si addition caused a lowering elastic modulus. The highest strength under compression load of Ti 5Si alloy was 1105 MPa, which was much higher than commercially pure titanium. Two alloys are more corrosion resistant than CP Ti, and Ti 5Si corrodes at a slower rate than Ti 5Nb alloy. The examination of biocompatibility involved the in vitro cytotoxicity experiment. The surfaces of the alloys demonstrated excellent growth conditions for MG-63 cells and the alloys did not display any toxic effects. Better mechanical and biocompatibility characteristics were displayed by the Ti5Si alloy. Ti5Si alloy, in conclusion, has enormous potential for use in orthopedic applications.