University of Kashan Journal of Nanostructures 2251-7871 13 1 2023 01 01 Synthesis of Silver Nanoparticles by Using Aloe Vera and Bio Application 59 65 112928 10.22052/JNS.2023.01.007 EN Mustafa H. N Department of Biomedical Engineering, University of Technology, Baghdad, Iraq Inas S.mohammed Department of Biomedical Engineering, University of Technology, Baghdad, Iraq Journal Article 2022 09 28 The present study aimed at the biosynthesis of silver nanoparticles by using aloe Vera leaves extract. Silver nanoparticles (Ag NPs) synthesized by the green method have shown several applications such as biomedical, anticancer, etc. Measurement of the size of silver nanoparticles by AFM (showing an average diameter of 54 nm), XRD and FE-SEM analyses. Four different concentrations (25, 50, 100, and 200 µg/ml) were prepared from the synthesized Ag NPs and examined for their antibacterial efficacy against both E.coli Furthermore, pseudomonas aeruginosa. Cytotoxicity was evaluated using MTT assays on (TCP -1013) cancer cell lines. As shown by the results, Ag NPs inhibit bacterial growth over the concentration range evaluated. High cytotoxicity against the investigated cancer cell line was also seen with all doses of Ag NPs tested, corroborating the antibacterial activity findings. There was a dosage relationship between Ag NPs antibacterial and anticancer properties. https://jns.kashanu.ac.ir/article_112928_e9d8300a7a51a12db0b2881a547d3c09.pdf